Although not all of these have been mentioned on this blog yet, this is a list of my all-time Favorites, all of which are worth reading.
The Amazing Adventures of Kavalier and Clay by Michael Chabon
Ready Player One by Ernest Cline
The Hours by Michael Cunningham
A Visit From the Goon Squad by Jennifer Egan
The Revised Fundamentals of Caregiving by Jonathan Evison
The Great Gatsby by F. Scott Fitzgerald
Gone Girl by Gillian Flynn
Extremely Loud and Incredibly Close by Jonathan Safran Foer
Carter Beats the Devil by Glen David Gold
The Other Boelyn Girl by Phillipa Gregory
The Many Lives and Secret Sorrow of Josephine B. by Sandra Gulland
Winter's Tale by Mark Helprin
Great House by Nicole Krauss
The History of Love by Nicole Krauss
Black Swan Green by David Mitchell
Gone With the Wind by Margaret Mitchell
Kafka on the Shore by Haruki Murakami
The Time Traveler's Wife by Audrey Niffenegger
Special Topics in Calamity Physics by Marissa Pessl
All is Vanity by Christina Schwarz
Stone Arabia by Dana Spiotta
The Help by Kathryn Stockett
The Financial Lives of the Poets by Jess Walter
The Interestings by Meg Wolitzer